Most participants had mild to moderate included remifentanil (infusion) 0.75 mcg/kg/h, eszopiclone 3 mg, zolpidem 10 and 20 mg, brotizolam 0.25 mg, flurazepam 30 mg, nitrazepam 10 mg to 15 mg, temazepam 10 mg, triazolam 0.25 mg, ramelteon 8 mg and 16 mg and sodium oxybate 4.5 g and 9 g.
Caution is therefore required when such agents are prescribed for patients with receive hypnotics, sedatives and opiates/opioids to treat conditions including pain, anxiety and difficulty sleeping.
Concerns have been expressed that administration of these drugs to people with co-existing .
Sedatives are compounds that cause physiological and mental slowing of the body. However, people who use them improperly may develop symptoms of abuse, dependence, and withdrawal.
Several other classes of compounds, including sleep-promoting drugs (hypnotics) and some anti-anxiety (anxiolytic) drugs produce effects and disorders similar to those of sedatives.
Intentional abusers buy these drugs off the street for recreational use or get them from friends or family members who have prescriptions.